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5. Infections
Daptomycin
BNF | BNFC | SPC

For occasional use when all other antimicrobials have proved ineffective

Linezolid
BNF | BNFC | SPC

pneumonia; complicated skin and soft-tissue infections caused by Gram-positive bacteria

Teicoplanin
BNF | BNFC | SPC

Clostridium difficile infection; Streptococcal or enterococcal endocarditis; Bone and joint infections

Colistimethate
BNF | BNFC | SPC

NICE TA276

Red drug when used for Cystic fibrosis indications only

Capreomycin
BNF | BNFC | SPC

Multi-resistant TB

Cycloserine
BNF | BNFC | SPC

Multi-resistant TB

Protionamide
BNF | BNFC | SPC

Multi-resistant TB

Temocillin
BNF | BNFC | SPC

ESBL-coliform septicaemia

Piperacillin / tazobactam
BNF | BNFC | SPC

Hospital-acquired pneumonia, septicaemia, complicated intra-abdominal infections, complicated infections involving the urinary tract or skin and soft tissues; Infections in neutropenic patients

Ticarcillin with clavulanic acid
BNF | BNFC | SPC

Infections due to pseudomonas and proteus spp

Ertapenem
BNF | BNFC | SPC

Only for one-off use for outpatient antibiotic treatment

Imipenem / Cilastatin
BNF | BNFC | SPC

Primaxim

Aerobic and anaerobic infections; hospital-acquired septicaemia

Meropenem
BNF | BNFC | SPC

Aerobic and anaerobic Gram-positive and Gram-negative infections; hospital-acquired septicaemia

Tigecycline
BNF | BNFC | SPC

For occasional use when all other antimicrobials have proved ineffective. Use must be authorised by an infectious disease consultant

Gentamicin
BNF | BNFC | SPC

Solution for injection

Infections; surgical prophylaxis

Tobramycin
BNF | BNFC | SPC
Moxifloxacin
BNF | BNFC | SPC

Tablets and injection only

MDR-TB. Respiratory and ID only

Amoxicillin
BNF | BNFC | SPC

SF susp - 125mg/5ml, 250mg/5ml

Capsules - 500mg

Capsules - 250mg - Only this dose if higher dose not tolerated or clinical reasons  

 

Azithromycin
BNF | BNFC | SPC

Tablets - 250mg, 500mg

 

Benzylpenicillin
BNF | BNFC | SPC

Inj - 600mg

Cefalexin
BNF | BNFC | SPC

Susp - 125mg/5ml, 250mg/5ml - For UTI in Children 

Susp - 500mg - UTI in pregnancy 

Ciprofloxacin
BNF | BNFC | SPC

Tablets - 250mg, 500mg 

Suspension - 250mg/5ml 

For pyelonephritis, acute prostatitis 

Clarithromycin
BNF | BNFC | SPC

Susp - 125mg/5ml, 250mg/5ml

Tablets - 250mg, 500mg 

Clindamycin
BNF | BNFC | SPC

Capsules - 150mg

For unresolving cellulitis, severe dental infection 

Co-amoxiclav
BNF | BNFC | SPC

Tablets - 375mg, 625mg - For persistent sinusitis, COPD where RF for resistance, pyelonephritis, human or animal bites, facial cellulitis 

SF Susp- 125/31, 250/62, 400/57 - for upper UTI in children 

Doxycycline
BNF | BNFC | SPC

Capsules - 100mg 

Disp Tablets - 100mg 

 

Erthromycin
BNF | BNFC | SPC

SF Susp - 125mg/5ml, 250mg/5ml - for under 12's where penicillin allergy 

Tablets 250mg - only where pregnant and penicillin allergy 

Flucloxacillin
BNF | BNFC | SPC

Capsules - 250mg(only where lower dose is clinically indicated), 500mg

Soln - 125mg/5ml, 250mg/5ml

SF Soln - 125mg/5ml, 250mg/5ml

Fosfomycin
BNF | BNFC | SPC

Sachet 3g 

Prescribe as Monuril brand 

Fusidic acid
BNF | BNFC | SPC

Cream - 2% 

Lymecycline
BNF | BNFC | SPC

Capsules - 408mg 

Metronidazole
BNF | BNFC | SPC

Tablets - 200mg, 400mg Lower dose where clinically indicated 

Susp - 200mg/5ml  

Nitofurantoin
BNF | BNFC | SPC

Tablet - 50mg, 100mg 

MR Capsules - 100mg For acute infections 

Ofloxacin
BNF | BNFC | SPC

Tablet - 200mg For actue prostatits 

Tablet - 400mg For PID

 

 

Oxytetracycline
BNF | BNFC | SPC

Tablets - 250mg 

Phenoxymethylpenicillin
BNF | BNFC | SPC

Tablets - 250mg 

Soln SF - 125mg/5ml, 250mg/5ml 

 

Pivmecillinam
BNF | BNFC | SPC

Tablets - 200mg 

Trimethoprim
BNF | BNFC | SPC

Tablets - 100mg, 200mg

SF Susp- 50mg/5ml 

Vancomycin
BNF | BNFC | SPC

Capsules - 125mg 

Rifaximin
BNF | BNFC | SPC

Tablets - 550mg 

Initiated by Consultant microbiologist or consultant gastroenterologist only in line with NICE TA 337 Rifaximin for preventing episodes of overt hepatic encephalopathy as an option for reducing the recurrence of episodes of overt hepatic encephalopathy in people aged 18 years or older.

Amphotericin
BNF | BNFC | SPC

Severe Systemic fungal Infections

Voriconazole
BNF | BNFC | SPC

Injections and tablets

For use by consultants in infectious disease. In cases of "fluconazole resistance"

Caspofungin
BNF | BNFC | SPC

Fungal infections

Invasive candidiasis in paediatrics

Invasive candidiasis/aspergillosis

Clotrimazole
BNF | BNFC | SPC

Vaginal Cream - 10%

Fluconazole
BNF | BNFC | SPC

Capsules - 50mg, 150mg

Susp - 50mg/5ml

Itraconazole
BNF | BNFC | SPC

Capsules - 100mg 

Miconazole
BNF | BNFC | SPC

Powder - 0% 

Terbinafine
BNF | BNFC | SPC

Tablets - 250mg 

Efavirenz
BNF | BNFC | SPC

HIV infection

Etravirine
BNF | BNFC | SPC

HIV infection

Nevirapine
BNF | BNFC | SPC

HIV infection

Rilpivirine
BNF | BNFC | SPC

HIV infection

Abacavir
BNF | BNFC | SPC

HIV infection

Didanosine
BNF | BNFC | SPC

HIV infection

Emtricitabine
BNF | BNFC | SPC

HIV Infection

Emtricitabine / rilpivirine / tenofovir
BNF | BNFC | SPC

Eviplera

Odefsey

HIV Infection

Emtricitabine / tenofovir alafenamide (Descovy)
BNF | BNFC | SPC

Descovy

HIV

 

Lamivudine
BNF | BNFC | SPC

HIV infection

Stavudine
BNF | BNFC | SPC

HIV infection

Tenofovir
BNF | BNFC | SPC
Zidovudine
BNF | BNFC | SPC

HIV infection

Enfuvirtide
BNF | BNFC | SPC

HIV Infection

Maraviroc
BNF | BNFC | SPC

HIV Infection

Raltegravir
BNF | BNFC | SPC

HIV infection

Atazanavir
BNF | BNFC | SPC

HIV Infection

Darunavir
BNF | BNFC | SPC

HIV infection

Fosamprenavir
BNF | BNFC | SPC

HIV infection

Indinavir
BNF | BNFC | SPC

HIV infection

Lopinavir
BNF | BNFC | SPC

HIV Infection

Nelfinavir
BNF | BNFC | SPC

HIV infection

Ritonavir
BNF | BNFC | SPC

HIV infection

Saquinavir
BNF | BNFC | SPC

HIV infection

Tipranavir
BNF | BNFC | SPC

HIV infection

Cidofovir
BNF | BNFC | SPC

Discontinued in UK 2014

Ganciclovir
BNF | BNFC | SPC

Cytomegalovirus; Herpes simplex infections

Valganciclovir
BNF | BNFC | SPC

CMV prevention

Adefovir
BNF | BNFC | SPC
Entecavir
BNF | BNFC | SPC
Telbivudine
BNF | BNFC | SPC

Not Approved NICE TA154

Boceprevir
BNF | BNFC | SPC

NICE TA253

Daclatasvir
BNF | BNFC | SPC
Elbasvir / grazoprevir
BNF | BNFC | SPC

Zepatier

NICE TA413

Ledipasvir / sofosbuvir
BNF | BNFC | SPC
Ombitasvir / paritaprevir / ritonavir
BNF | BNFC | SPC
Telaprevir
BNF | BNFC | SPC
Simeprevir
BNF | BNFC | SPC

Not Approved: NICE TA361 (in combination with sofosbuvir)

Amantadine
BNF | BNFC | SPC

Not Approved NICE TA168, TA158

Palivizumab
BNF | BNFC | SPC

Respiratory syncytial virus

Ribavirin
BNF | BNFC | SPC

NICE TA75, TA106, TA300

Aciclovir
BNF | BNFC | SPC

Tablets - 200mg, 400mg, 800mg 

Valaciclovir
BNF | BNFC | SPC

Tablets - 500mg 

Paromomycin
BNF | BNFC | SPC

Leishmaniasis

Artesunate
BNF | BNFC | SPC

Treatment of Malaria

Other Antimalarials
BNF | BNFC | SPC

Tees prescribing grey list

Medication for malaria prophylaxis is not reimbursible by the NHS. 

Prescription only medicines for malaria prophylaxis should be prescribed privately and other medications can be purchased via a local community pharmacy.

Useful prescribing information - a guide for prescribers (51 downloads)

Mepacrine
BNF | BNFC | SPC

Giardiasis

Sodium stibogluconate
BNF | BNFC | SPC

Leishmaniasis

Pentamidine
BNF | BNFC | SPC

Pneumocystis pneumonia

Diethylcarbamazine
BNF | BNFC | SPC

Wuchereria bancrofti infections; brugia malayi infections; loa loa infections

Ivermectin
BNF | BNFC | SPC

Unlicensed Oral formulations

Chronic strongyloides infection; cutaneous larva migrans; scabies

 

Levamisole
BNF | BNFC | SPC

Roundworm infections

Praziquantel
BNF | BNFC | SPC

Tapeworms

Mebendazole
BNF | BNFC | SPC

Chewable tablets - 100mg 

Susp - 100mg/5ml

Combined Diphtheria, Tetanus, Acellular Pertussis and Inactivated Poliomyelitis Vaccine (Repevax/ Infanrix IPV)
BNF | BNFC | SPC
Combined Diphtheria, Tetanus, Acellular Pertussis, Inactivated Polio, HIB and Hepatitis B vaccine (DTaP/IPV/Hib/HepB –Infanrix hexa®)
BNF | BNFC | SPC
Combined Diptheria, Tetanus, Acellular Pertussis & Inactivated Poliomyelitis (dTap/IPV) Vaccine (Boostrix®-IPV/Repevax®)
BNF | BNFC | SPC
Combined Haemophilus Influenza Type B + Meningococcal Group C Conjugate Vaccine (Hib + MenC - Mentorix)
BNF | BNFC | SPC
Combined Hepatitis A + B Vaccines
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Combined Hepatitis A + Typhoid Vaccines (Hepatyrix and ViATM)
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Combined Low Dose Diphtheria, Tetanus and Inactivated Polio Vaccine (Td/ IPV - Revaxis)
BNF | BNFC | SPC
Hepatitis A Vaccines
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Hepatitis B Vaccine for Infants born on or after 1st August 2017
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Hepatitis B Vaccines
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Human Papillomavirus (Types 6,11,16,18) (Recombinant, adsorbed) (HPV) Vaccine (Gardasil)
BNF | BNFC | SPC
Influenza (seasonal flu) Vaccines
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Measles, Mumps and Rubella Vaccine (MMR)
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Meningococcal B Protein Vaccine 4CMenB (Bexsero)
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Pneumococcal Vaccine (NECSAT 2018/002)
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Quadrivalent Meningococcal Conjugate Vaccines (Menveo and Nimenrix)
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Rotavirus Vaccine (Oral Suspension)
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Shingles (Herpes Zoster) Vaccine
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation

Typhoid Vaccines (Typhim Vi, Typherix and Vivotif)
BNF | BNFC | SPC

Patient Group Directions - NECS Medicines Optimisation